Antimicrobial Resistance will reduce global annual GDP by 3.8% by 2050: WHO

Antimicrobial Resistance (AMR) will reduce global annual GDP by 3.8% by 2050, the World Health Organisation (WHO) said on Friday and added that it could push 24 million more people into extreme poverty. "New global estimates show that in 2019, nearly 5 million human deaths worldwide were associated with bacterial AMR, of which 1.3 million human deaths were directly attributable to bacterial AMR. In a high-impact scenario, AMR will reduce global annual GDP by 3.8 per cent by 2050. If left unchecked, in the next decade, it could result in a GDP shortfall of USD3.4 trillion annually, pushing 24 million more people into extreme poverty," WHO Regional Director for South-East Asia Dr. Poonam Khetrapal Singh said in a statement.

The WHO made the announcement to highlight the urgent need for sustained multisectoral action to prevent and contain antimicrobial resistance (AMR) during World Antimicrobial Awareness Week (WAAW). AMR occurs when bacteria, viruses, fungi, and parasites change over time and no longer respond to medicines, making infections harder to treat and increasing the risk of disease spread, severe illness, and death. The WHO said that preventing and combating AMR has been one of eight Flagship Priorities of the WHO South-East Asia Region since 2014. All Member States continue to implement national action plans to address AMR, and in each Member State, a multi-sectoral working group or coordination committee on AMR has been established, in alignment with the Global Action Plan on AMR, adopted in 2015, it added.

Most Member States continue to implement national monitoring systems for resistance pathogens and antimicrobial consumption as well as foster stewardship in human health. All Member States are enrolled in the Global Antimicrobial Resistance Surveillance System (GLASS) AMR and the South-East Asia Region is the only WHO Region in which all countries carry out the annual Tracking AMR Country Self-Assessment Surveys, which this year was expanded to include the environment sector for the first time. The WHO further said that countries of the region continue to face an array of multisectoral challenges "Such challenges include unsafe disposal of medicine and pharmaceutical waste, inadequate regulation of antimicrobial use in food production, insufficient infection prevention and control in health facilities, and inadequate access to safe water, sanitation and hygiene in homes and health facilities," it said adding that the climate crisis is creating additional breeding grounds for antimicrobial-resistant bacteria.

In recognition of these and other challenges, for this year's WAAW, the One Health Quadripartite-- which includes WHO, the Food and Agriculture Organization of the United Nations (FAO), the World Organization for Animal Health (WOAH), and the United Nations Environment Programme (UNEP)-- is highlighting the urgent need to increase One Health action to address AMR, with the theme 'preventing antimicrobial resistance together. The statement from the WHO further disclosed its priorities as-- one, accelerating implementation of national multisectoral action plans, for which adequate, sustained and reliable financing must be allocated; two, improving surveillance of antimicrobial-resistant infections and strengthening laboratory capacity which is critical to know the true extent of the problem, and to effectively target energy and resources; three, developing and enforcing regulations on the appropriate use of antimicrobial medicines in all relevant sectors (human, animal, plant, food safety, and environment) while ensuring such regulations promote and facilitate access for appropriate antimicrobial use; and four, stepping-up investments in adequate water, sanitation and hygiene, a critical health intervention in and of itself, but which will also have a significant impact on the tsunami of environmental pollution and contamination-driven antimicrobial resistance. It also said that the development of a new antimicrobial can take 10-15 years and cost more than USD 1 billion.

"For the foreseeable future, we must accelerate One Health action while continuing to increase national, Regional, international, and global awareness and support - precisely as Indonesia achieved during its presidency of the G20 group of nations, which resulted in a Call to Action to increase One Health efforts to address AMR." It also reaffirmed its commitment to support all the countries of the region to prevent and contain AMR together, across sectors, partners, stakeholders, and the public through the WAAW and after that.